Serpent Isle is a tropical island in the Malphigian Sea that lies roughly 15 miles south of the city of Kathros. The island's name comes from the unusual profusion of dangerous snakes that inhabit it, including anacondas, asps, bushmasters, boa constrictors, coral snakes, kraits, fer-de-lance, horned vipers, king cobras, pythons, puff adders, and sea snakes.
The isle is thick with nearly impassable jungle vegetation, but trails wind around the entire perimeter of the island and in to a central clearing. On the east side of the island is a lagoon and the remains of a village, one the native islanders were forced to abandoned when the snake infestation became overwhelming.